Computational Methods for Multiple Level Linear Mixed-effects Models
نویسندگان
چکیده
In an earlier paper we provided easily-calculated expressions for the gradient of the profiled log-likelihood and log-restricted-likelihood for single-level mixed-effects models. We also showed how this gradient is related to the update of an ECME (expectation conditional maximization either) algorithm for such single level models. In this paper we extend those results to mixed-effects models with multiple nested levels of random effects.
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